ASBMR 2020

New scientific studies presented at the ASBMR American Society for Bone and Mineral Research Congress 2020:

1. A novel non-ionizing technology for bone densitometry and fracture risk prediction

Conversano, D. Ciardo, F.A. Lombardi, P. Pisani, S. Casciaro

National Research Council, Institute of Clinical Physiology, Lecce, Italy

Highlight:

This work reviews all the available literature about REMS technology published until May 2020; given the available scientific evidences, the authors conclude that REMS technology allows both to measure BMD and to provide insight into the bone micro-architecture without the use of X-rays, overcoming the main DXA limitations and opening up the possibility of early diagnosis of osteoporosis, of a wider access to bone health assessment also for specific categories such as paediatric patients and pregnant women.

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2. New technology REMS demonstrated good accuracy for the diagnosis of osteoporosis defined by DXA, in Brazilian adult women

D.M. Amos Amorim, E.N. Sakane, S.Setsuo Maeda, M. Lazaretti Castro

Federal University of Sao Paulo, Sao Paulo, Brazil

Highlight:

This study presents the results of a DXA-REMS comparison on 343 brazilian women. These results highlight on the one hand a good correlation between the two technologies in terms of sensitivity and specificity for both sites (femur and spine) and on the other hand a good level of precision and repeatability for REMS technology evaluated through the parameter RMS-CV (%) computed on both the anatomical sites of reference.

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3. REMS technology a new diagnostic approach in patients with spine artifacts

M.D. Tomai Pitinca, C.Caffarelli, S.Gonnelli

Department of Medicine, Surgery and Neuroscience, University of Siena, Siena, Italy

Highlight:

This study compares densitometric estimates of DXA and REMS methods on 86 women with spine conditions (osteoarthritis, vertebral fractures, vertebroplasty) which are known to alter DXA BMD introducing an overestimation of such a parameter. For those women, while the measurements obtained on the femur with both techniques were very similar and highly correlated between each other, for the lumbar site REMS estimates were significantly lower than DXA ones hence evaluated as more accurate for patients with pathologies or conditions which have a negative influence on DXA results reliability.

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4. Radiofrequency Echographic Multi Spectrometry (REMS) technology repeatability and precision assessment for short-term monitoring application

Pisani, F. Lombardi, D. Ciardo, F.Conversano, S. Casciaro

National Research Council, Institute of Clinical Physiology, Lecce, Italy

Highlight:

This study evaluates REMS technology intra-operator, inter-operator and inter-device repeatability of REMS for short-term therapeutic follow-up of patients with breast cancer. The three types of repeatability were evaluated as very good and these features allowed to detect a significant BMD decrease in patients undergoing an Aromatase Inhibitors (AI) treatment as well as a significant BMD increase in patients under both AI and Denosumab treatment just six months after the first examination.

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