Radiofrequency echographic multi spectrometry for the prediction of incident fragility fractures: A 5-year follow-up study

Giovanni Adami1, Giovanni Arioli2, Gerolamo Bianchi3, Maria Luisa Brandi4, Carla Caffarelli5, Luisella Cianferotti4, Davide Gatti1, Giuseppe Girasole3, Stefano Gonnelli5, Monica Manfredini2, Maurizio Muratore6, Eugenio Quarta6, Laura Quarta6

Published: Bone. 2020 May;134:115297

Highlight:

The identification of patients at risk for fragility fractures who may benefit from osteoporosis treatments is a challenge to clinicians. With this prospective observational study, the authors investigated the effectiveness of the T-score values provided by Radiofrequency Echographic Multi-Spectrometry (REMS) in the identification of patients at risk for incident osteoporotic fractures, comparing the performance of REMS with the Dual-energy X-ray Absorptiometry (DXA) one in a 5-years follow-up.

The studied population were over 1500 women from 30 to 90 years old who underwent REMS and DXA scans at femoral and vertebral sites. Among the findings of this study, a high agreement between REMS- and DXA-measured bone mineral density (BMD) values was observed. As concerning fragility fractures, a relationship between lower T-score values and higher fracture rate was observed, as expected.

Considering the reference T-score threshold value of −2.5 to distinguish between osteoporotic and non-osteoporotic patients, REMS showed higher sensitivity than DXA at the vertebral site in the identification of incident fragility fracture (65.1% versus 57.7%, respectively), whereas the performance were comparable between techniques for the femoral site. REMS T-score resulted an effective predictor of the occurrence of incident fragility fractures, representing a valuable approach to enhance osteoporosis diagnosis in clinical routine.

 

1 Rheumatology Unit, Department of Medicine, University of Verona, Verona, Italy
2 Department of Neurosciences and Rehabilitation, “Carlo Poma” Hospital, ASST-Mantova, Mantova, Italy
3 SC Rheumatology, ASL 3 Genovese, Genoa, Italy
4 Department of Experimental and Clinical Biomedical Sciences, University of Florence, Metabolic Bone Diseases Unit, University Hospital of Florence, Florence, Italy
5 Department of Medicine, Surgery and Neurosciences, University of Siena, Siena, Italy
6 O.U. of Rheumatology, “Galateo” Hospital, San Cesario di Lecce ASL-LE, Lecce, Italy

REMS in Springer book

REMS in Springer book

Pulse-Echo Measurements of Bone Tissues. Techniques and Clinical Results at the Spine and Femur The Advances in Experimental Medicine and Biology book series (AEMB, volume 1364) now provides a review of the available pulse-echo approaches for the quantitative...

read more
EULAR 2022

EULAR 2022

New scientific studies presented at the recent European Congress of Rheumatology EULAR 2022:   Radiofrequency Echographic Multi Spectrometry (REMS) for the assessment of femoral bone health in a male population Fiorella Anna Lombardi1, Paola Pisani1, Alessandra...

read more
Anorexia and bone density

Anorexia and bone density

Assessment of bone mineral density in young women with anorexia nervosa by means of Radiofrequency Echographic Multispectrometry (REMS) technology. Caffarelli1, M. D. Tomai Pitinca1, A. Al Refaie1, M. De Vita1, E. Giglio1, P. Pisani2, S. Gonnelli1   1Dept. of...

read more

    Contact Us

    More info or book a demo.



    Position*

    *Required fields



    This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

    Copyright © 2021 - Echolight S.p.a Tutti i diritti riservati